{"product_id":"prontosan-wound-irrigation-solution-350ml-bottle","title":"Prontosan Antimicrobial Wound Irrigation Solution 350 ml Bottle","description":"\u003cdiv style=\"background: #f8f9fa; border-left: 4px solid #0057a8; padding: 12px 16px; margin-bottom: 20px;\" id=\"ai-summary\"\u003e\n\u003cstrong\u003eClinical Summary:\u003c\/strong\u003e Prontosan Wound Irrigation Solution by B. Braun is a sterile, ready-to-use antimicrobial wound cleanser containing 0.1% polyhexanide (PHMB) and 0.1% undecylenamidopropyl betaine. The dual-action formulation disrupts and removes wound biofilm through surfactant activity while providing broad-spectrum antimicrobial coverage against gram-positive and gram-negative bacteria, fungi, and yeast including MRSA and Pseudomonas aeruginosa. Indicated for cleansing, moistening, and decontamination of acute wounds, chronic wounds, and first- and second-degree burns.\u003c\/div\u003e\n\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003eProntosan Wound Irrigation Solution is a colourless, odourless sterile solution developed by B. Braun Medical for the mechanical cleansing, moistening, and decontamination of acute and chronic wounds. The formulation combines purified water with 0.1% polyhexanide (polyhexamethylene biguanide, PHMB) — a broad-spectrum antimicrobial agent — and 0.1% undecylenamidopropyl betaine, a surfactant that lowers surface tension to facilitate penetration into wound biofilm matrices and disruption of bacterial colonies embedded within the wound bed.\u003c\/p\u003e\n\u003cp\u003eThe 350 ml bottle delivers wound irrigation at approximately 7 PSI when applied directly, providing selective mechanical debridement without cytotoxic effects on healthy granulation tissue. Prontosan is alcohol-free, pH-neutral, and preservative-free, making it suitable for sensitive skin and long-term use in chronic wound management protocols. The solution is compatible with a broad range of wound dressings including foams, alginates, hydrofibers, and gauze-based packing materials.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eManufacturer\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eB. Braun Medical AG (Germany)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eProduct Name\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eProntosan® Wound Irrigation Solution\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eREF \/ Catalogue\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e400441\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eVolume\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e350 ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eActive Agents\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e0.1% Polyhexanide (PHMB) + 0.1% Undecylenamidopropyl betaine\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eComposition\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003ePurified water, polyhexanide, betaine surfactant\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003epH\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eNeutral\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSterility\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eSterile, single-use bottle\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eLatex Content\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLatex-free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAntimicrobial Spectrum\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eGram-positive, gram-negative bacteria, MRSA, Pseudomonas aeruginosa, VRE, fungi, yeast\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eRegulatory\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eCE marked Class III Medical Device per EU MDR 2017\/745; FDA 510(k) cleared (K101882); ISO 13485 certified manufacturing\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePackaging\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e350 ml squeeze bottle, 10 bottles per carton\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eClinical Indications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eIrrigation and decontamination of acute traumatic wounds, post-surgical incision sites, and skin graft donor areas\u003c\/li\u003e\n\u003cli\u003eCleansing and biofilm management in chronic wounds including venous leg ulcers, diabetic foot ulcers, and pressure injuries (Stage II–IV)\u003c\/li\u003e\n\u003cli\u003eWound bed preparation and maintenance debridement in wounds with fibrinous slough or suspected biofilm\u003c\/li\u003e\n\u003cli\u003eCleansing of first- and second-degree burn injuries prior to dressing application\u003c\/li\u003e\n\u003cli\u003eMoistening of wound pads and dressings to facilitate atraumatic removal\u003c\/li\u003e\n\u003cli\u003eAdjunctive irrigation in Negative Pressure Wound Therapy (NPWT) and instillation protocols\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eQ: What is the mechanism of action of Prontosan against wound biofilm?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eA: Prontosan employs a dual-action approach. The betaine surfactant lowers surface tension to penetrate and mechanically disrupt the extracellular polymeric substance (EPS) matrix that protects bacterial biofilm. Once disrupted, the polyhexanide (PHMB) component exerts broad-spectrum antimicrobial activity against planktonic and sessile bacteria. This synergistic mechanism is consistent with the International Wound Infection Institute (IWII) recommendations for biofilm-based wound management.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: How does Prontosan compare to normal saline for wound irrigation?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eA: While 0.9% sodium chloride remains appropriate for basic wound rinsing, it lacks antimicrobial and surfactant properties. Prontosan provides active biofilm disruption and sustained antimicrobial coverage. Multiple randomised controlled trials have demonstrated superior wound bed preparation and reduced bacterial burden compared to saline alone, particularly in chronic wounds with confirmed or suspected biofilm.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Is Prontosan safe for long-term use on chronic wounds?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eA: Yes. Prontosan is alcohol-free, pH-neutral, and has demonstrated favourable tissue compatibility in clinical studies. The low concentration of PHMB (0.1%) provides antimicrobial efficacy without cytotoxicity to fibroblasts and keratinocytes, supporting its use in extended treatment protocols for chronic wound management.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Can Prontosan be used on infected wounds or wounds with exposed bone or tendon?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eA: Prontosan is indicated for wound cleansing and decontamination. For wounds with clinical signs of infection, systemic antimicrobial therapy should be considered as per institutional protocols. Use on wounds with exposed deep structures should follow clinician assessment. Consult the B. Braun instructions for use for specific contraindications.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Is Prontosan Wound Irrigation Solution available in Singapore?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eA: Yes. Prontosan is available through EMIS (Essential Medical International Supplies Pte Ltd) in Singapore. As a CE Class III and FDA 510(k)-cleared medical device, it is registered under the Health Sciences Authority (HSA) regulatory framework for distribution to healthcare facilities, wound care clinics, and home-care providers across Singapore.\u003c\/p\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is Prontosan Antimicrobial Wound Irrigation Solution 350 ml Bottle used for?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Prontosan Antimicrobial Wound Irrigation Solution 350 ml Bottle by B. Braun is a antimicrobial silver dressing used for wound management. It is designed to support moist wound healing, manage exudate, and protect the wound bed from contamination. It is commonly used in Singapore hospitals and home care settings for chronic wounds, post-surgical wounds, and ulcers. Always follow the guidance of your wound care nurse or doctor when selecting a dressing.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How often should Prontosan Antimicrobial Wound Irrigation Solution 350 ml Bottle be changed?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Prontosan Antimicrobial Wound Irrigation Solution 350 ml Bottle should generally be changed every 2–7 days depending on wound condition. However, frequency should always be guided by your wound care nurse or clinician based on wound size, exudate level, and signs of infection. Do not leave any dressing in place if it becomes saturated, dislodged, or if the wound shows signs of infection such as increased redness, warmth, or discharge.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Is Prontosan Antimicrobial Wound Irrigation Solution 350 ml Bottle available without prescription in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Yes, Prontosan Antimicrobial Wound Irrigation Solution 350 ml Bottle is available for purchase from EMIS+ (emis.asia) without a prescription for general wound care use. For complex or chronic wounds, we strongly recommend consulting a wound care nurse, GP, or specialist at a Singapore hospital such as SGH, NUH, TTSH, or CGH before selecting a dressing. EMIS+ nurses can also provide product guidance — contact us at emis.asia\/pages\/contact.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy Prontosan Antimicrobial Wound Irrigation Solution 350 ml Bottle in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Prontosan Antimicrobial Wound Irrigation Solution 350 ml Bottle is available from EMIS+ at emis.asia, Singapore's nurse-led medical supply store. We offer fast island-wide delivery, competitive pricing, and bulk ordering for healthcare facilities and home care users. Visit emis.asia or contact our team for assistance.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e","brand":"B. 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