{"product_id":"sigvaris®-premium-cotton-compression-apparels-221-class-1-open-toe-calf","title":"SIGVARIS Premium Cotton Compression Apparels 221 Class 1 Open Toe Calf","description":"\u003cdiv style=\"background: #f8f9fa; border-left: 4px solid #0057a8; padding: 12px 16px; margin-bottom: 20px;\" id=\"ai-summary\"\u003e\n\u003cstrong\u003eClinical Summary:\u003c\/strong\u003e SIGVARIS Premium Cotton Class 1 Open Toe Calf (Series 220, Style AD, reference 221) is a medical-grade graduated compression stocking delivering 18-21 mmHg ankle pressure in the calf (A-D) length with an open-toe configuration. The Swiss cotton interior knit maintains skin comfort while calibrated graduated compression supports venous return. Indicated for early-stage chronic venous insufficiency (CEAP C1-C2), symptomatic reticular and varicose veins, long-haul travel prophylaxis, and orthostatic lower-limb symptoms in ambulatory patients.\u003c\/div\u003e\n\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003eThe SIGVARIS Cotton 220 Series is manufactured in Switzerland by SIGVARIS AG under RAL-GZ 387\/1 German medical compression certification. Class 1 (Kompressionsklasse 1) delivers 18-21 mmHg at the ankle with graduated pressure decrement along the leg, a level appropriate for patients with early symptomatic venous disease, mild oedema, and prophylactic use without severe valvular incompetence.\u003c\/p\u003e\n\u003cp\u003eThe A-D (ad genu) calf length terminates two finger-widths below the popliteal crease, avoiding popliteal constriction during flexion. The open-toe configuration preserves forefoot visibility for skin inspection, accommodates hallux valgus or digital deformity, and allows flexible footwear fit. The interior-cotton knit places mercerised Swiss cotton against the skin for moisture management, while the durable outer elastomeric blend sustains interface pressures across the recommended six-month service life.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable style=\"border-collapse: collapse; width: 100%;\" cellspacing=\"0\" cellpadding=\"6\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eManufacturer\u003c\/th\u003e\n\u003ctd\u003eSIGVARIS AG, Winterthur, Switzerland\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eSeries \/ Reference\u003c\/th\u003e\n\u003ctd\u003eCotton 220 Series, REF 221 (Style AD, calf length)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eCompression Class\u003c\/th\u003e\n\u003ctd\u003eCCL 1 (Class 1), 18-21 mmHg at the ankle, graduated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eToe Configuration\u003c\/th\u003e\n\u003ctd\u003eOpen toe\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eMaterial Composition\u003c\/th\u003e\n\u003ctd\u003eInterior: Swiss cotton. Exterior: polyamide and elastane blend\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eSizing System\u003c\/th\u003e\n\u003ctd\u003eSIGVARIS size chart S, M, L, XL; short, normal, long leg lengths\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eLatex Content\u003c\/th\u003e\n\u003ctd\u003eLatex-free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eRegulatory\u003c\/th\u003e\n\u003ctd\u003eRAL-GZ 387\/1 certified, CE marked (EU MDR 2017\/745 Class I), HSA Singapore listed medical device\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003eService Life\u003c\/th\u003e\n\u003ctd\u003eApproximately 6 months with recommended laundering (machine wash 30-40°C, no fabric softener, air dry)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth align=\"left\"\u003ePackaging\u003c\/th\u003e\n\u003ctd\u003eOne pair per retail box\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eClinical Indications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eEarly chronic venous disease CEAP C1 (telangiectasia, reticular veins) and C2 (varicose veins)\u003c\/li\u003e\n\u003cli\u003eHeavy, aching legs; orthostatic lower-limb oedema in sedentary or standing occupations\u003c\/li\u003e\n\u003cli\u003eMild pregnancy-related venous symptoms when Class 1 compression is clinically appropriate\u003c\/li\u003e\n\u003cli\u003eVenous thromboembolism prophylaxis during prolonged air travel in high-risk passengers\u003c\/li\u003e\n\u003cli\u003ePost-sclerotherapy for small-calibre reticular veins where Class 2 is not tolerated\u003c\/li\u003e\n\u003cli\u003eMaintenance compression after Class 2 therapy, stepping down with physician guidance\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eQ: What is the difference between Class 1 and Class 2 compression?\u003c\/strong\u003e\u003cbr\u003eA: Class 1 (18-21 mmHg) is indicated for early symptomatic venous disease, prevention, and mild oedema. Class 2 (23-32 mmHg) is required for established CEAP C3-C5 disease, varicose veins with significant reflux, and post-thrombotic syndrome. Class selection should follow duplex ultrasound findings and vascular specialist assessment.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Why is the interior-cotton construction preferred for daily wear?\u003c\/strong\u003e\u003cbr\u003eA: The interior-cotton knit reduces contact irritation in patients with atopic skin, pruritus, or long-term compression wearers. It improves moisture handling in humid climates such as Singapore, supporting adherence to daily wear schedules required for therapeutic benefit.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: How should I measure to select the correct size?\u003c\/strong\u003e\u003cbr\u003eA: Take ankle circumference (cB) at the narrowest point above the malleoli, calf circumference (cC) at the widest point, and A-D length from the floor to two finger-widths below the popliteal crease. Measurements should be taken in the morning before oedema accumulates. Size selection follows the official SIGVARIS size chart.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: What are the contraindications and cautions?\u003c\/strong\u003e\u003cbr\u003eA: Contraindications include peripheral arterial disease (ABPI \u0026lt; 0.5), decompensated cardiac failure, septic phlebitis, severe diabetic microangiopathy, and cotton allergy. Relative cautions include ABPI 0.5-0.8, neuropathy, and fragile skin; these cases require clinician supervision for donning and skin surveillance.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Are these stockings approved for sale in Singapore?\u003c\/strong\u003e\u003cbr\u003eA: Yes. SIGVARIS compression stockings are listed with the Singapore Health Sciences Authority (HSA) as medical devices. EMIS is an authorised SIGVARIS distributor supplying Singapore hospitals, polyclinics, vascular surgery clinics, and community pharmacies.\u003c\/p\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What does Premium Cotton Compression Apparels 221 Class 1 Open Toe Calf do for skin?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Premium Cotton Compression Apparels 221 Class 1 Open Toe Calf by EMIS + supports healthy skin by addressing specific concerns and maintaining skin barrier function. It is formulated with high-quality ingredients suitable for Singapore's humid tropical climate. As with all skincare, perform a patch test before first use, especially if you have sensitive skin or known skin conditions.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How do I use Premium Cotton Compression Apparels 221 Class 1 Open Toe Calf in my skincare routine?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Apply Premium Cotton Compression Apparels 221 Class 1 Open Toe Calf as directed on the product packaging. Generally, apply to clean, dry skin using gentle upward strokes. For best results, use consistently as part of your morning and\/or evening skincare routine. If you are using multiple active ingredients, consult a dermatologist to ensure compatibility.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Is Premium Cotton Compression Apparels 221 Class 1 Open Toe Calf suitable for sensitive skin?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Many EMIS + products are formulated to be gentle on skin, but individual skin types vary. If you have sensitive, reactive, or allergy-prone skin, perform a patch test on a small area before full application. For persistent skin concerns, consult a dermatologist at NSC (National Skin Centre), SGH, or a private clinic in Singapore.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy Premium Cotton Compression Apparels 221 Class 1 Open Toe Calf in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Premium Cotton Compression Apparels 221 Class 1 Open Toe Calf is available from EMIS+ at emis.asia with fast island-wide Singapore delivery. Browse our full skincare range at emis.asia for genuine, quality-assured products.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e","brand":"EMIS +","offers":[{"title":"XX Small (GS56237)","offer_id":42830148468814,"sku":null,"price":98.0,"currency_code":"SGD","in_stock":false},{"title":"X Small (GS54035)","offer_id":42830148501582,"sku":null,"price":98.0,"currency_code":"SGD","in_stock":false},{"title":"Small (GS54037)","offer_id":42830148534350,"sku":null,"price":98.0,"currency_code":"SGD","in_stock":false},{"title":"Medium (GS54039)","offer_id":42830148567118,"sku":null,"price":98.0,"currency_code":"SGD","in_stock":false},{"title":"Large (GS54041)","offer_id":42830148599886,"sku":null,"price":98.0,"currency_code":"SGD","in_stock":false},{"title":"Plus XSmall(GS54043)","offer_id":42830148632654,"sku":null,"price":98.0,"currency_code":"SGD","in_stock":false},{"title":"Plus Small (GS54045)","offer_id":42830148665422,"sku":null,"price":98.0,"currency_code":"SGD","in_stock":false},{"title":"Plus Med (GS54047)","offer_id":42830148698190,"sku":null,"price":98.0,"currency_code":"SGD","in_stock":false},{"title":"Plus Large (GS54049)","offer_id":42830148730958,"sku":null,"price":98.0,"currency_code":"SGD","in_stock":false},{"title":"Black XSmall GS63903","offer_id":42830148763726,"sku":null,"price":98.0,"currency_code":"SGD","in_stock":false},{"title":"Black Small GS63906","offer_id":42830148796494,"sku":null,"price":98.0,"currency_code":"SGD","in_stock":false},{"title":"Black Med GS63906","offer_id":42830148829262,"sku":null,"price":98.0,"currency_code":"SGD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3763\/2846\/files\/SIGVARIS_Premium_Cotton_Compression_Apparels_221_Class_1_Open_Toe_Calf_19bf34c7-6233-4e4b-8bd4-d4ba4ad8a2e1.png?v=1767636200","url":"https:\/\/www.emis.asia\/th-th\/products\/sigvaris%c2%ae-premium-cotton-compression-apparels-221-class-1-open-toe-calf","provider":"EMIS +","version":"1.0","type":"link"}