{"product_id":"visiopro-probiotics-30s-450-billion-live-probio","title":"VisioPro Probiotics 30 Sachets – 450 Billion Live Probiotics (Clinic Exclusive)","description":"\u003cdiv style=\"background: #f8f9fa; border-left: 4px solid #0057a8; padding: 12px 16px; margin-bottom: 20px;\" id=\"ai-summary\"\u003e\n\u003cstrong\u003eClinical Summary:\u003c\/strong\u003e VisioPro Probiotics is a high-potency probiotic food supplement containing the De Simone Formulation — eight strains of live bacteria delivering 450 billion CFU per sachet. Originally developed by Professor Claudio De Simone, this formulation is supported by over 60 published human clinical studies and is indicated for the dietary management of irritable bowel syndrome (IBS), ulcerative colitis (UC), and ileal pouch-associated conditions.\u003c\/div\u003e\n\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003eVisioPro Probiotics 30 Sachets delivers the clinically validated De Simone Formulation in a clinic-exclusive high-potency format. Each sachet provides 450 billion colony-forming units (CFU) of eight distinct bacterial strains spanning Lactobacillus, Bifidobacterium, and Streptococcus genera. This formulation is classified as a probiotic food supplement and is distributed in Singapore through authorised clinical channels by Hyphen Group Pte Ltd.\u003c\/p\u003e\n\u003cp\u003eThe De Simone Formulation is the only probiotic preparation backed by more than 60 peer-reviewed human clinical trials, including randomised controlled studies published in journals such as Gastroenterology, The American Journal of Gastroenterology, and Alimentary Pharmacology and Therapeutics. VisioPro is manufactured under strict pharmaceutical-grade conditions with cold-chain logistics to maintain viability of the live bacterial cultures from production through to patient consumption.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable style=\"border-collapse: collapse; width: 100%;\" cellspacing=\"0\" cellpadding=\"8\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eFormulation\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eDe Simone Formulation (original, developed by Prof. Claudio De Simone)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eProduct Form\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003ePowder sachets, 30 sachets per box\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCFU Count\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e450 billion live bacteria per sachet\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eBacterial Strains (8 strains)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLactobacillus paracasei, L. plantarum, L. acidophilus, L. delbrueckii subsp. bulgaricus, Bifidobacterium longum, B. infantis, B. breve, Streptococcus thermophilus\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eDistributor (Singapore)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eHyphen Group Pte Ltd\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eChannel\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eClinic Exclusive — available through authorised healthcare practitioners only\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eRefrigerate at 2–8°C. Cold-chain shipping required to maintain viability\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAllergen Information\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eContains traces of milk and soy (from fermentation medium). Gluten-free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eRegulatory\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eClassified as a food supplement. Registered with the Singapore Food Agency (SFA). Manufactured under ISO 22000 food safety management and cGMP pharmaceutical-grade conditions\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eClinical Evidence\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e60+ published human clinical studies on the De Simone Formulation\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePackaging\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eIndividual foil sachets in a refrigerated carton, 30 sachets per box\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eClinical Indications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eDietary management of irritable bowel syndrome (IBS) — supported by RCTs demonstrating reduction in abdominal bloating, pain, and stool irregularity\u003c\/li\u003e\n\u003cli\u003eAdjunctive dietary management in mild-to-moderate ulcerative colitis (UC) — evidence from gastroenterology trials on mucosal barrier function\u003c\/li\u003e\n\u003cli\u003eMaintenance of remission in ileal pouch-anal anastomosis (IPAA) patients — pouchitis prevention as referenced in European Crohn's and Colitis Organisation (ECCO) guidelines\u003c\/li\u003e\n\u003cli\u003eRestoration of gut microbiota diversity following antibiotic therapy or gastrointestinal infection\u003c\/li\u003e\n\u003cli\u003eSupport for intestinal barrier integrity and modulation of mucosal immune responses via IgA-mediated pathways\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eQ: What distinguishes VisioPro from standard over-the-counter probiotics?\u003c\/strong\u003e\u003cbr\u003eA: VisioPro delivers 450 billion CFU per sachet — substantially higher than standard consumer probiotics which typically range from 1 to 50 billion CFU. The De Simone Formulation is the only multi-strain probiotic preparation with more than 60 published human clinical trials. This level of clinical evidence is a key differentiator from generic probiotic supplements available in retail pharmacies.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Why does VisioPro require refrigeration?\u003c\/strong\u003e\u003cbr\u003eA: The live bacterial cultures in VisioPro are sensitive to temperature degradation. Maintaining cold-chain storage at 2–8°C preserves the viability and CFU count of the eight bacterial strains through to the expiry date. The World Gastroenterology Organisation (WGO) guidelines on probiotics note that storage conditions directly affect probiotic potency and clinical efficacy.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Is VisioPro suitable for patients with lactose intolerance?\u003c\/strong\u003e\u003cbr\u003eA: VisioPro contains traces of milk from the bacterial fermentation medium. Patients with confirmed lactose intolerance should consult their prescribing practitioner, although the residual lactose content per sachet is minimal. The product is gluten-free and does not contain artificial colours or preservatives.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: How should VisioPro be administered?\u003c\/strong\u003e\u003cbr\u003eA: Each sachet should be dissolved in a non-carbonated, non-hot beverage (water, juice, or milk below 37°C) and consumed immediately. Hot liquids will destroy the live bacterial cultures. The standard clinical dosage is 1–2 sachets per day, or as directed by the prescribing healthcare professional, depending on the indication being managed.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Can Singapore clinic patients purchase VisioPro directly?\u003c\/strong\u003e\u003cbr\u003eA: VisioPro is classified as a clinic-exclusive product in Singapore and is distributed by Hyphen Group Pte Ltd through authorised healthcare practitioners. Patients can purchase through their treating clinic or via authorised online platforms such as EMIS, which maintains cold-chain delivery within Singapore to ensure product integrity.\u003c\/p\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What are the benefits of VisioPro Probiotics 30 Sachets – 450 Billion Live Probiotics (Clinic Exclusive) for digestive health?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"VisioPro Probiotics 30 Sachets – 450 Billion Live Probiotics (Clinic Exclusive) by Hyphen promotes gut microbiome diversity, supports digestive comfort, and strengthens the gut-immune axis. For individuals with digestive concerns such as IBS, bloating, or irregular bowel habits, targeted gut health supplementation may complement a balanced diet and lifestyle. Always consult a doctor or dietitian before starting supplements for digestive conditions.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Who should take VisioPro Probiotics 30 Sachets – 450 Billion Live Probiotics (Clinic Exclusive)?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"VisioPro Probiotics 30 Sachets – 450 Billion Live Probiotics (Clinic Exclusive) may benefit adults seeking to support digestive health, those recovering from antibiotic use, individuals with irregular bowel habits, or those with conditions affecting gut microbiome balance. It is not a substitute for medical treatment. Consult your GP or gastroenterologist — available at SGH, NUH, Mount Elizabeth, and Raffles Hospital in Singapore — for personalised advice.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How should I take VisioPro Probiotics 30 Sachets – 450 Billion Live Probiotics (Clinic Exclusive) for best results?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Follow the dosage instructions on the VisioPro Probiotics 30 Sachets – 450 Billion Live Probiotics (Clinic Exclusive) packaging or as directed by your healthcare provider. Consistency is key — most gut health supplements take 4–8 weeks of regular use to show measurable benefits. Store as directed on the label. Do not exceed the recommended daily dose.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy VisioPro Probiotics 30 Sachets – 450 Billion Live Probiotics (Clinic Exclusive) in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"VisioPro Probiotics 30 Sachets – 450 Billion Live Probiotics (Clinic Exclusive) is available at EMIS+ (emis.asia) with fast Singapore island-wide delivery. We carry a curated range of clinically-informed digestive health supplements. Visit emis.asia or contact our team for product recommendations.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e","brand":"Hyphen","offers":[{"title":"Default Title","offer_id":43232650002510,"sku":null,"price":129.36,"currency_code":"SGD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3763\/2846\/files\/VisioPro_Probiotics_Clinic_Exclusive.png?v=1767035409","url":"https:\/\/www.emis.asia\/th-th\/products\/visiopro-probiotics-30s-450-billion-live-probio","provider":"EMIS +","version":"1.0","type":"link"}