{"product_id":"glycolic-10-renew-overnight","title":"SkinCeuticals Glycolic 10 Renew Overnight","description":"\u003cdiv style=\"background: #f8f9fa; border-left: 4px solid #0057a8; padding: 12px 16px; margin-bottom: 20px;\" id=\"ai-summary\"\u003e\n\u003cstrong\u003eClinical Summary:\u003c\/strong\u003e SkinCeuticals Glycolic 10 Renew Overnight is a leave-on alpha-hydroxy acid (AHA) treatment formulated with 10% glycolic acid at a free acid value of 10% and 2% phytic acid, designed to accelerate epidermal cell turnover, reduce corneocyte cohesion, and deliver measurable improvements in skin radiance, texture, and tone. In an 8-week clinical study, the formula produced a 36% average improvement in radiance, 37% improvement in skin texture, and 19% improvement in skin tone. It is clinically indicated for dull, photoaged, congested, or hyperpigmented skin and is compatible with structured anti-ageing protocols prescribed at Singapore dermatology and aesthetic medicine clinics.\u003c\/div\u003e\n\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003eSkinCeuticals Glycolic 10 Renew Overnight is a leave-on exfoliant formulated with sugar-cane-derived glycolic acid — the smallest-molecular-weight AHA, enabling the deepest penetration relative to other hydroxy acids — combined with phytic acid, a natural antioxidant chelating agent from legumes and seeds. The 10% free acid value (FAV) concentration operates at the threshold validated in multiple peer-reviewed studies to produce clinically meaningful exfoliation without compromising barrier integrity in most skin types. Glycolic acid at this concentration disrupts calcium-mediated desmosome cohesion in the stratum corneum, accelerating shedding of accumulated corneocytes, and simultaneously stimulates epidermal growth factor receptor (EGFR) signalling to promote keratinocyte proliferation and collagen precursor synthesis in the dermis.\u003c\/p\u003e\n\u003cp\u003eThe addition of 2% phytic acid provides dual benefit: chelation of pro-oxidant metal ions that contribute to free radical generation, and mild tyrosinase inhibition that synergises with glycolic acid's exfoliation to reduce post-inflammatory hyperpigmentation and solar lentigines. The emollient base containing jojoba esters, sunflower seed wax, and tocopherol supports barrier repair during the nocturnal dosing period. Dermatologists and aesthetic practitioners in Singapore incorporate this product into multi-modal treatment protocols for photodamage, melasma, and pre-treatment skin preparation prior to chemical peels or laser resurfacing.\u003c\/p\u003e\n\u003ch2\u003eFormulation Specifications\u003c\/h2\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 14px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"background: #f1f5f9;\"\u003e\n\u003ctd style=\"padding: 8px 12px; border: 1px solid #ddd; font-weight: 600; width: 38%;\"\u003eManufacturer\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px; border: 1px solid #ddd;\"\u003eSkinCeuticals (L'Oréal Dermatological Beauty)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 8px 12px; border: 1px solid #ddd; font-weight: 600;\"\u003eProduct Reference\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px; border: 1px solid #ddd;\"\u003eGlycolic 10 Renew Overnight\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background: #f1f5f9;\"\u003e\n\u003ctd style=\"padding: 8px 12px; border: 1px solid #ddd; font-weight: 600;\"\u003ePrimary Active — Glycolic Acid\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px; border: 1px solid #ddd;\"\u003e10% free acid value (sugar-cane-derived AHA)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 8px 12px; border: 1px solid #ddd; font-weight: 600;\"\u003eSecondary Active — Phytic Acid\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px; border: 1px solid #ddd;\"\u003e2% (antioxidant, chelating, tyrosinase-inhibiting)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background: #f1f5f9;\"\u003e\n\u003ctd style=\"padding: 8px 12px; border: 1px solid #ddd; font-weight: 600;\"\u003eAlso Contains\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px; border: 1px solid #ddd;\"\u003eSalicylic Acid (BHA), Jojoba Esters, Sunflower Seed Wax, Tocopherol (Vitamin E)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 8px 12px; border: 1px solid #ddd; font-weight: 600;\"\u003eFormat\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px; border: 1px solid #ddd;\"\u003eLeave-on overnight treatment cream, 50 mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background: #f1f5f9;\"\u003e\n\u003ctd style=\"padding: 8px 12px; border: 1px solid #ddd; font-weight: 600;\"\u003eClinical Evidence\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px; border: 1px solid #ddd;\"\u003e8-week study: 36% radiance, 37% texture, 19% skin tone improvement\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 8px 12px; border: 1px solid #ddd; font-weight: 600;\"\u003eApplication\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px; border: 1px solid #ddd;\"\u003eEvenings only — AHA increases UV sensitivity; SPF 30+ AM use mandatory\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background: #f1f5f9;\"\u003e\n\u003ctd style=\"padding: 8px 12px; border: 1px solid #ddd; font-weight: 600;\"\u003eFragrance \/ Paraben Status\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px; border: 1px solid #ddd;\"\u003eFragrance-free, paraben-free\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 8px 12px; border: 1px solid #ddd; font-weight: 600;\"\u003eRegulatory Note (Singapore)\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px; border: 1px solid #ddd;\"\u003eAHA cosmetic product; HSA Circular on AHA cosmetics specifies photosensitivity labelling. Distributed via authorised medical channels including EMIS Singapore.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eClinical Indications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhotodamage and solar lentigines:\u003c\/strong\u003e 10% glycolic acid accelerates corneocyte desquamation to reduce sun spots in Fitzpatrick II–IV skin types within 4–8 weeks of consistent nocturnal use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMelasma adjunct therapy:\u003c\/strong\u003e Used as maintenance exfoliant between clinic-based peel or laser sessions in Singapore; phytic acid provides complementary tyrosinase inhibition.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkin texture refinement:\u003c\/strong\u003e Disrupts the hyperkeratotic surface layer in patients with rough, congested, or enlarged-pore presentations — consistent with the 37% texture improvement endpoint.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePre-procedure skin preparation:\u003c\/strong\u003e Applied nightly 4–6 weeks prior to medium-depth TCA peels or ablative laser to pre-thin stratum corneum and improve peel penetration uniformity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAcne and congestion:\u003c\/strong\u003e Reduces comedonal burden via follicular keratolysis; trace salicylic acid provides complementary lipid-soluble penetration into the pilosebaceous unit.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCombination with retinoids:\u003c\/strong\u003e Alternated on separate nights with retinol in physician-directed regimens for complementary mechanisms — AHA exfoliation plus cell-turnover stimulation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Is it safe to use 10% glycolic acid nightly?\u003c\/strong\u003e\u003cbr\u003eA: Introduction at 2–3 nights per week for the first 2–4 weeks is recommended before progressing to nightly use. Transient tingling is expected and does not indicate intolerance; persistent erythema warrants reducing frequency and seeking dermatologist review.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Does Glycolic 10 Renew Overnight replace professional chemical peels?\u003c\/strong\u003e\u003cbr\u003eA: No. Home-use AHA at 10% FAV produces superficial exfoliation in the stratum corneum and upper epidermis. Professional peels at Singapore clinic settings reach deeper epidermal and papillary dermal levels. The overnight treatment functions as maintenance and preparation between professional treatments.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Why is daily SPF mandatory when using this product?\u003c\/strong\u003e\u003cbr\u003eA: AHAs increase UV sensitivity by reducing stratum corneum thickness. The HSA Singapore and FDA both require photosensitivity risk labelling on AHA cosmetics. Omitting SPF counteracts the product's brightening objectives. Minimum SPF 30 PA+++ is recommended by Singapore dermatology practice standards.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Can patients with sensitive skin or rosacea use this?\u003c\/strong\u003e\u003cbr\u003eA: Patients with active rosacea, compromised barriers, or active inflammatory acne should seek dermatologist assessment before use. Patch testing on the jawline for 48 hours prior to full-face application is advisable for any patient with known skin reactivity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Where is Glycolic 10 Renew Overnight available in Singapore?\u003c\/strong\u003e\u003cbr\u003eA: Available through authorised SkinCeuticals medical channels in Singapore, including EMIS (Essential Medical International Supplies Pte Ltd). Not available in general consumer pharmacies.\u003c\/p\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is SkinCeuticals Glycolic 10 Renew Overnight used for?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"SkinCeuticals Glycolic 10 Renew Overnight by SkinCeuticals is an ostomy care product designed to support stoma management and protect peristomal skin. It is suitable for use with colostomy, ileostomy, and urostomy pouching systems. For personalised advice on your pouching system, consult a Wound, Ostomy and Continence (WOC) nurse at SGH, NUH, CGH, or TTSH in Singapore.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Is SkinCeuticals Glycolic 10 Renew Overnight suitable for all stoma types — colostomy, ileostomy, and urostomy?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Most SkinCeuticals stoma care products are designed to be compatible with all stoma types. However, the right product depends on your individual stoma location, output type, and skin condition. An enterostomal therapist (ET nurse) at a Singapore hospital can help you select the most appropriate products for your specific pouching system.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How do I use SkinCeuticals Glycolic 10 Renew Overnight correctly?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Always refer to the product instructions included with SkinCeuticals Glycolic 10 Renew Overnight. In general, ensure peristomal skin is clean and dry before application, measure your stoma accurately, and change your pouching system every 1–3 days or when leakage is suspected. If you experience peristomal skin irritation, soreness, or persistent leakage, contact a WOC nurse or EMIS+ team for advice.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy SkinCeuticals Glycolic 10 Renew Overnight in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"SkinCeuticals Glycolic 10 Renew Overnight is available from EMIS+ at emis.asia — Singapore's trusted nurse-led stoma supply store. We stock a comprehensive range of ostomy products with fast island-wide delivery. Bulk orders for home care and nursing facilities are welcome. Contact us at emis.asia\/pages\/contact.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e","brand":"SkinCeuticals","offers":[{"title":"50 ml","offer_id":43041857077326,"sku":"SKC_0005","price":155.0,"currency_code":"SGD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3763\/2846\/files\/SkinCeuticals_Glycolic_10_Renew_Overnight_2f37e6bd-1bf4-46a7-be59-96d92c6a582f.png?v=1767125887","url":"https:\/\/www.emis.asia\/zh\/products\/glycolic-10-renew-overnight","provider":"EMIS +","version":"1.0","type":"link"}