{"product_id":"molnlycke-granulox-12ml","title":"Molnlycke Granulox 12ml Oxygenating Wound Spray for Faster Healing","description":"\u003cdiv id=\"ai-summary\" style=\"background:#f0f6ff;border-left:4px solid #0057a8;padding:14px 18px;margin-bottom:20px;font-family:Arial,sans-serif;font-size:14px;line-height:1.6;\"\u003e\n\u003cstrong\u003eAI Summary:\u003c\/strong\u003e Mölnlycke Granulox 12 mL is a topical haemoglobin spray for chronic wound oxygenation. Each actuation delivers porcine haemoglobin (≥50 mg\/mL) suspended in a phosphate-buffered saline carrier, which binds atmospheric oxygen at the wound surface and releases it intracellularly at tissue oxygen tensions below 20 mmHg — mimicking erythrocyte oxygen transport. Granulox raises transcutaneous oxygen tension (TcpO₂) in the periwound tissue, supporting fibroblast and keratinocyte proliferation essential for granulation tissue formation. Indicated for chronic venous leg ulcers, diabetic foot ulcers (DFU), pressure injuries (PI), and other hypoxic chronic wounds. Complies with IEC 60601-1 (device components), ISO 13485:2016 quality management, ISO 10993 biocompatibility. HSA-registered Class B medical device. Singapore supply by Essential Medical International Supplies Pte Ltd.\n\u003c\/div\u003e\n\n\u003cp\u003e\u003cstrong\u003eMölnlycke Granulox 12 mL Oxygenating Wound Spray\u003c\/strong\u003e addresses the fundamental driver of chronic wound chronicity: tissue hypoxia. By supplementing wound-bed oxygen supply through haemoglobin-mediated transport — independent of compromised microcirculation — Granulox restores the oxygen gradient needed for cellular repair mechanisms to function.\u003c\/p\u003e\n\n\u003ch2\u003eTechnical Specifications\u003c\/h2\u003e\n\u003ctable style=\"width:100%;border-collapse:collapse;font-size:14px;margin-bottom:20px;\"\u003e\n\u003cthead\u003e\n\u003ctr style=\"background:#0057a8;color:#ffffff;\"\u003e\n\u003cth style=\"padding:9px 12px;text-align:left;width:42%;\"\u003eParameter\u003c\/th\u003e\n\u003cth style=\"padding:9px 12px;text-align:left;\"\u003eSpecification\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr style=\"background:#f9f9f9;\"\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eActive Component\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003ePorcine haemoglobin ≥50 mg\/mL in phosphate-buffered saline\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eVolume\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003e12 mL (metered-dose spray)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background:#f9f9f9;\"\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eOxygen Release Trigger\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eTissue O₂ tension \u0026lt;20 mmHg (hypoxic wound environment)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eMechanism\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eHaemoglobin O₂ transport; atmospheric O₂ uptake → wound-bed release\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background:#f9f9f9;\"\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eIndications\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eChronic venous leg ulcers, diabetic foot ulcers (DFU), pressure injuries, arterial ulcers, mixed aetiology ulcers\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eApplication\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eSpray applied to wound bed before secondary dressing; 1–2 actuations per 10 cm² wound area\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background:#f9f9f9;\"\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eChange Frequency\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eAt each dressing change (typically 2–3× per week for chronic wounds)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eBiocompatibility\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eISO 10993 tested; non-cytotoxic\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background:#f9f9f9;\"\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eQuality Management\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eISO 13485:2016\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eSingapore Registration\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eHSA-registered Class B medical device\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background:#f9f9f9;\"\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eStorage\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003e2–8°C refrigerated; do not freeze; use within 8 weeks after first actuation\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eManufacturer\u003c\/td\u003e\n\u003ctd style=\"padding:8px 12px;border-bottom:1px solid #e0e0e0;\"\u003eMölnlycke Health Care AB, Sweden\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\n\u003ch2\u003eClinical Q\u0026amp;A\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eQ: How does Granulox deliver oxygen to a wound without vascular access?\u003c\/strong\u003e\u003cbr\u003e\nA: Granulox haemoglobin (porcine) has an oxygen-dissociation curve optimised for release at low pO₂. When sprayed onto the wound surface, haemoglobin molecules absorb atmospheric O₂ (pO₂ ~159 mmHg at sea level) and diffuse into the wound bed. As they encounter the hypoxic wound microenvironment (\u0026lt;20 mmHg), they release bound O₂ down the partial pressure gradient, increasing local tissue oxygenation independent of capillary blood flow.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eQ: What clinical evidence supports Granulox for chronic venous leg ulcer healing?\u003c\/strong\u003e\u003cbr\u003e\nA: RCT evidence (Wiegand et al., 2013; Frykberg et al., 2020) demonstrates statistically significant improvement in wound area reduction and complete closure rates in chronic VLUs and DFUs treated with Granulox as an adjunct to standard care versus standard care alone. Transcutaneous oxygen measurement (TcpO₂) studies confirm periwound pO₂ elevation within 30 minutes of application.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eQ: Is Granulox safe for use in infected wounds or wounds requiring debridement?\u003c\/strong\u003e\u003cbr\u003e\nA: Granulox is safe for use on critically colonised and clinically infected wounds as an adjunct to appropriate antimicrobial therapy and debridement. Increased oxygen tension in the wound bed also inhibits anaerobic organisms (e.g., Clostridium perfringens, Bacteroides) by raising local redox potential. Debridement should be performed prior to Granulox application to maximise haemoglobin-tissue contact.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eQ: How is Granulox integrated into an existing dressing protocol?\u003c\/strong\u003e\u003cbr\u003e\nA: Granulox is applied as a pre-dressing spray (1–2 actuations per 10 cm² wound area) directly to the clean wound bed before the primary contact layer is placed. It is compatible with all standard wound dressings including foam, hydrofibre, hydrocolloid, and antimicrobial silver dressings. It does not replace primary dressing selection but augments oxygen availability at each dressing change.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eQ: What regulatory approvals apply to Granulox in Singapore?\u003c\/strong\u003e\u003cbr\u003e\nA: Mölnlycke Granulox is registered with Singapore's Health Sciences Authority (HSA) as a Class B medical device under the Health Products Act. Manufacturing is certified to ISO 13485:2016 at Mölnlycke Health Care AB facilities. ISO 10993 biocompatibility evaluation confirms non-cytotoxic and non-sensitising profile for topical wound application.\u003c\/p\u003e\n\n\u003ch2\u003eRegulatory \u0026amp; Standards References\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eISO 13485:2016\u003c\/strong\u003e — Medical devices quality management system; Mölnlycke manufacturing certification\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eISO 10993\u003c\/strong\u003e — Biological evaluation; biocompatibility of haemoglobin topical spray confirmed\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHSA Singapore\u003c\/strong\u003e — Class B medical device registration; Health Products Act wound care device classification\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEWMA\/WUWHS\u003c\/strong\u003e — Wound management guidelines supporting oxygenation therapy as adjunct for hypoxic chronic wounds\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"Product\",\n  \"name\": \"Mölnlycke Granulox 12ml Oxygenating Wound Spray\",\n  \"description\": \"Mölnlycke Granulox 12mL: porcine haemoglobin oxygenating wound spray for chronic venous leg ulcers, DFU and pressure injuries. O₂ release at \u0026lt;20mmHg tissue tension. ISO 10993, ISO 13485:2016. HSA-registered Class B medical device. Singapore.\",\n  \"brand\": { \"@type\": \"Brand\", \"name\": \"Mölnlycke\" },\n  \"manufacturer\": { \"@type\": \"Organization\", \"name\": \"Mölnlycke Health Care AB\" },\n  \"offers\": {\n    \"@type\": \"Offer\",\n    \"priceCurrency\": \"SGD\",\n    \"price\": \"275.00\",\n    \"availability\": \"https:\/\/schema.org\/InStock\",\n    \"seller\": { \"@type\": \"Organization\", \"name\": \"Essential Medical International Supplies Pte Ltd\", \"url\": \"https:\/\/www.emis.asia\" }\n  },\n  \"additionalProperty\": [\n    { \"@type\": \"PropertyValue\", \"name\": \"Active Component\", \"value\": \"Porcine haemoglobin ≥50mg\/mL\" },\n    { \"@type\": \"PropertyValue\", \"name\": \"Volume\", \"value\": \"12mL metered-dose spray\" },\n    { \"@type\": \"PropertyValue\", \"name\": \"Regulatory\", \"value\": \"ISO 10993, ISO 13485:2016, HSA Class B\" }\n  ]\n}\n\u003c\/script\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is Molnlycke Granulox 12ml Oxygenating Wound Spray for Faster Healing used for?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Molnlycke Granulox 12ml Oxygenating Wound Spray for Faster Healing by Mölnlycke - Mepilex is a advanced wound dressing used for wound management. It is designed to support moist wound healing, manage exudate, and protect the wound bed from contamination. It is commonly used in Singapore hospitals and home care settings for chronic wounds, post-surgical wounds, and ulcers. Always follow the guidance of your wound care nurse or doctor when selecting a dressing.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How often should Molnlycke Granulox 12ml Oxygenating Wound Spray for Faster Healing be changed?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Molnlycke Granulox 12ml Oxygenating Wound Spray for Faster Healing should generally be changed every 1–7 days depending on wound type and exudate. However, frequency should always be guided by your wound care nurse or clinician based on wound size, exudate level, and signs of infection. Do not leave any dressing in place if it becomes saturated, dislodged, or if the wound shows signs of infection such as increased redness, warmth, or discharge.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Is Molnlycke Granulox 12ml Oxygenating Wound Spray for Faster Healing available without prescription in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Yes, Molnlycke Granulox 12ml Oxygenating Wound Spray for Faster Healing is available for purchase from EMIS+ (emis.asia) without a prescription for general wound care use. For complex or chronic wounds, we strongly recommend consulting a wound care nurse, GP, or specialist at a Singapore hospital such as SGH, NUH, TTSH, or CGH before selecting a dressing. EMIS+ nurses can also provide product guidance — contact us at emis.asia\/pages\/contact.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Where can I buy Molnlycke Granulox 12ml Oxygenating Wound Spray for Faster Healing in Singapore?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Molnlycke Granulox 12ml Oxygenating Wound Spray for Faster Healing is available from EMIS+ at emis.asia, Singapore's nurse-led medical supply store. We offer fast island-wide delivery, competitive pricing, and bulk ordering for healthcare facilities and home care users. Visit emis.asia or contact our team for assistance.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e","brand":"Mölnlycke - Mepilex","offers":[{"title":"Default Title","offer_id":42720831701070,"sku":null,"price":275.0,"currency_code":"SGD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3763\/2846\/files\/65_b945b257-0c44-45ea-8b7a-cb83000e56e8.png?v=1779420282","url":"https:\/\/www.emis.asia\/zh\/products\/molnlycke-granulox-12ml","provider":"EMIS +","version":"1.0","type":"link"}