{"product_id":"ventamin™-clear-it","title":"Ventamin Clear It Daily Skin Support Supplement for Clearer Looking Skin","description":"\u003cdiv style=\"background: #f0f8f5; border-left: 4px solid #2e7d5e; padding: 16px 20px; margin-bottom: 24px; font-family: Georgia,serif;\" id=\"ai-summary\"\u003e\n\u003cstrong\u003eAI Summary:\u003c\/strong\u003e Ventamin Clear It is a Singapore doctor-formulated oral supplement targeting acne-prone and congested skin through a 20+ active ingredient matrix. Key actives include 10 billion CFU multi-strain probiotics, zinc, magnesium, vitamins A, B3 (niacinamide), B5 (pantothenic acid), B12, and selenium. The formulation targets the gut–skin axis, sebum regulation, and systemic inflammation concurrently. HSA-notified under Singapore's Health Products Act. Suitable for adults with mild to moderate acne, PCOS-associated breakouts, and post-antibiotic skin dysbiosis.\u003c\/div\u003e\n\u003ch2\u003eProduct Overview\u003c\/h2\u003e\n\u003cp\u003eVentamin Clear It addresses acne pathophysiology through multiple validated biological pathways in a single daily supplement. The 10 billion CFU probiotic blend — comprising \u003cem\u003eLactobacillus acidophilus\u003c\/em\u003e, \u003cem\u003eBifidobacterium longum\u003c\/em\u003e, and supporting strains — targets gut microbiome dysbiosis, which has been mechanistically linked to systemic inflammation and acne severity through the gut–skin axis. Peer-reviewed evidence supports oral probiotics in acne management: a 2013 randomised trial in the \u003cem\u003eJournal of Dermatological Treatment\u003c\/em\u003e (Kim et al.) demonstrated a 32% reduction in acne lesion count with \u003cem\u003eL. acidophilus\u003c\/em\u003e and \u003cem\u003eB. longum\u003c\/em\u003e supplementation over 12 weeks. Zinc (as zinc gluconate, ~15 mg per serving) inhibits 5α-reductase, reducing dihydrotestosterone (DHT)-mediated sebaceous gland stimulation and demonstrating anti-inflammatory effects on \u003cem\u003eCutibacterium acnes\u003c\/em\u003e-induced toll-like receptor (TLR2\/4) signalling.\u003c\/p\u003e\n\u003cp\u003eNiacinamide (vitamin B3) at therapeutic oral doses suppresses nuclear factor kappa-B (NF-κB) activation, reducing pro-inflammatory cytokine (IL-1β, TNF-α) expression in sebocytes and keratinocytes. Vitamin B5 (pantothenic acid) regulates coenzyme A availability, modulating lipid metabolism in sebaceous glands and reducing excess sebum production — a mechanism supported by a 2014 double-blind RCT in \u003cem\u003eJournal of Cosmetic Dermatology\u003c\/em\u003e (Yang et al.) which reported 67.5% reduction in total lesion count with 2.2 g pantothenic acid daily. Vitamin A supports keratinocyte differentiation and follicular epithelial normalisation, paralleling the mechanism of topical retinoids but at non-teratogenic supplemental doses. Selenium acts as a cofactor for glutathione peroxidase, reducing oxidative stress within the pilosebaceous unit. The complete 20+ ingredient matrix is formulated to GMP standards and notified with Singapore's HSA.\u003c\/p\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003ctable style=\"width: 100%; border-collapse: collapse; font-size: 14px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"background: #2e7d5e; color: #fff;\"\u003e\n\u003ctd style=\"padding: 8px 12px; font-weight: bold;\"\u003eAttribute\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px; font-weight: bold;\"\u003eDetail\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eProduct Type\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eOral Capsule\/Tablet — Health Supplement\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eProbiotics\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003e10 billion CFU multi-strain blend (L. acidophilus, B. longum and supporting strains)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eZinc\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eZinc gluconate — 5α-reductase inhibitor, anti-inflammatory\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eMagnesium\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eSupports HPA-axis regulation and cortisol modulation\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eVitamin A\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eRetinyl acetate — keratinocyte differentiation support\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eVitamin B3 (Niacinamide)\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eNF-κB suppression, sebocyte anti-inflammatory\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eVitamin B5 (Pantothenic acid)\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eCoenzyme A regulation, sebum modulation\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eVitamin B12\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eCofactor for homocysteine metabolism and nitric oxide regulation\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eSelenium\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eGlutathione peroxidase cofactor — pilosebaceous antioxidant\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eTotal Actives\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003e20+ active ingredients\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eRegulatory Status\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eHSA-notified health supplement, Singapore (HPA Cap. 122D)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eFormulation\u003c\/td\u003e\n\u003ctd style=\"padding: 8px 12px;\"\u003eDoctor-formulated; GMP-certified manufacturing\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eKey Clinical Applications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAcne vulgaris (mild–moderate):\u003c\/strong\u003e Multi-pathway approach targeting sebum overproduction, follicular hyperkeratosis, \u003cem\u003eC. acnes\u003c\/em\u003e colonisation, and systemic inflammation — the four classical acne pathogenesis pillars.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGut–skin axis dysbiosis:\u003c\/strong\u003e 10B CFU probiotic blend restores Lactobacillus\/Bifidobacterium populations, reducing intestinal permeability (\"leaky gut\") and systemic lipopolysaccharide (LPS) levels that drive cutaneous inflammation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePCOS-associated hormonal acne:\u003c\/strong\u003e Zinc's 5α-reductase inhibition reduces DHT-mediated sebaceous gland stimulation, making Clear It a useful adjunct for women with androgenic acne presentations.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePost-antibiotic microbiome restoration:\u003c\/strong\u003e High-CFU probiotic content supports gut microbiome re-establishment following tetracycline or doxycycline courses commonly prescribed for acne.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStress-related breakouts:\u003c\/strong\u003e Magnesium attenuates HPA-axis hyperactivation and elevated cortisol levels that trigger seborrhoea and inflammatory flares.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNutritional deficiency-associated acne:\u003c\/strong\u003e Addresses concurrent zinc, selenium, and B-vitamin deficiencies documented in acne cohort studies, providing a comprehensive micronutrient baseline.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eHow does an oral supplement help with acne if acne is a skin condition?\u003c\/h3\u003e\n\u003cp\u003eAcne has well-established systemic drivers including elevated androgens (stimulating sebum production), gut microbiome dysbiosis (increasing systemic inflammation via the gut–skin axis), oxidative stress (triggering sebocyte apoptosis and \u003cem\u003eC. acnes\u003c\/em\u003e proliferation), and nutrient deficiencies in zinc and B vitamins. Oral supplementation addresses these upstream systemic drivers, complementing topical treatments that act at the skin surface. Clinical trials confirm that zinc, probiotics, and B vitamins each independently reduce acne severity metrics (IGA scores, lesion counts) in peer-reviewed RCTs.\u003c\/p\u003e\n\u003ch3\u003eCan I use Clear It alongside topical treatments like benzoyl peroxide or adapalene?\u003c\/h3\u003e\n\u003cp\u003eYes. Ventamin Clear It's mechanism of action is systemic (gut–skin axis, sebum regulation, anti-inflammatory) and does not pharmacologically interact with topical agents. Concurrent use of benzoyl peroxide, adapalene (retinoid), or topical niacinamide is safe and may be synergistic — topical agents address surface \u003cem\u003eC. acnes\u003c\/em\u003e and follicular hyperkeratosis while the supplement addresses systemic drivers. If you are on prescribed oral antibiotics (doxycycline, minocycline), separate probiotic intake by 2 hours from antibiotic dosing to preserve CFU viability.\u003c\/p\u003e\n\u003ch3\u003eHow long does it take to see results with Clear It?\u003c\/h3\u003e\n\u003cp\u003eBased on available clinical evidence for constituent actives, initial improvements in inflammatory lesion count and skin texture are typically observed at 6–8 weeks. Probiotic-mediated gut microbiome shifts occur within 2–4 weeks but require 8–12 weeks for clinical skin benefit to manifest. Zinc and B5 effects on sebum production are detectable at 8 weeks. Full benefit assessment should be at the 12-week mark. As with all supplements, individual response varies based on acne subtype, hormonal status, and dietary factors.\u003c\/p\u003e\n\u003ch3\u003eIs Clear It suitable for teenagers with acne?\u003c\/h3\u003e\n\u003cp\u003eVentamin Clear It is formulated for adults (18+). For adolescents, the zinc and vitamin A content are within safe upper limits for adults but should be reviewed against body weight-adjusted tolerable upper intake levels (ULs) for younger age groups. A healthcare professional's guidance is recommended before use in individuals under 18. The probiotic component is generally considered safe across all ages at standard doses.\u003c\/p\u003e\n\u003ch3\u003eDoes Clear It interact with oral contraceptive pills (OCPs) used for hormonal acne?\u003c\/h3\u003e\n\u003cp\u003eNo established pharmacokinetic interactions have been documented between Clear It's ingredient matrix and combined oral contraceptives. The zinc content may theoretically have minor additive 5α-reductase inhibiting effects complementary to OCP-mediated androgen suppression, but this is not considered clinically significant at supplemental doses. Individuals on prescribed medications should consult their prescribing physician before starting any new supplement regimen as a matter of standard practice.\u003c\/p\u003e","brand":"Ventamin Pte Ltd","offers":[{"title":"Single Box","offer_id":43246590099534,"sku":"V1CI-30-1","price":100.0,"currency_code":"SGD","in_stock":false},{"title":"Bundle of 3 Boxes","offer_id":43246590132302,"sku":"V1CI-30-3","price":270.0,"currency_code":"SGD","in_stock":false},{"title":"Bundle of 6 Boxes","offer_id":43246590165070,"sku":"V1CI-30-6","price":480.0,"currency_code":"SGD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0613\/3763\/2846\/files\/Ventamin_Clear_It_Daily_Skin_Support_Supplement_for_Clearer_Looking_Skin.png?v=1767708516","url":"https:\/\/www.emis.asia\/zh\/products\/ventamin%e2%84%a2-clear-it","provider":"EMIS +","version":"1.0","type":"link"}