SRW Nrv2 Stress Relief and Relaxation Supplement for Calm and Sleep Support

Product Overview

SRW Nrv2 addresses the neurobiological underpinnings of stress and disrupted sleep through three complementary pharmacological pathways. PhytoCann BP delivers beta-caryophyllene, a bicyclic sesquiterpene present in black pepper and cannabis that selectively binds the CB2 cannabinoid receptor without psychotropic activity. CB2 receptor activation modulates neuroinflammation, reduces anxiety-related behaviour in preclinical models, and supports GABAergic tone — the primary inhibitory neurotransmitter system involved in anxiolysis and sedation. Sensoril® Ashwagandha (Withania somnifera, standardised to ≥10% withanolides by HPLC, Natreon Inc.) has been evaluated in six published randomised double-blind placebo-controlled trials demonstrating reductions in serum cortisol (up to 27.9%), perceived stress scale (PSS) scores, and C-reactive protein, alongside improvements in insomnia index, sleep onset latency, and overall sleep quality after 60 days.

Maizinol, derived from Zea mays (corn) leaf extract, contributes compounds with melatonin-pathway activity including precursor indoles and phytomelatonin analogues that support circadian signalling at the suprachiasmatic nucleus. By reinforcing endogenous melatonin receptor activation at physiological doses, Maizinol aims to improve sleep onset without the next-day grogginess associated with pharmacological melatonin doses. The formula was developed under the scientific guidance of Dr. Fatah Ahtesh PhD, a specialist in natural pharmaceuticals, and is manufactured in a GMP-certified facility in New Zealand meeting TGA (Therapeutic Goods Administration) manufacturing standards.

Specifications

Key Applications

• Attenuating chronic psychosocial stress and cortisol dysregulation in professionals, caregivers, and individuals with high occupational demands in Singapore's urban setting
• Supporting sleep onset and sleep quality in adults with mild insomnia, sleep onset delay, or irregular circadian rhythms without prescription hypnotic dependence risk
• Managing situational anxiety and nervous system overactivation associated with major life events, examination periods, or significant work pressure
• Supporting nervous system recovery in burnout, post-viral fatigue, and adrenal stress states through cortisol normalisation
• Adjunct support in integrative stress-management programmes alongside psychotherapy, mindfulness, and lifestyle interventions

Frequently Asked Questions

Q: What clinical evidence supports Sensoril Ashwagandha for stress and sleep?
A: Sensoril® is the most clinically studied ashwagandha extract, with six published RCTs. A 2019 double-blind RCT (Langade et al., Cureus) in 60 adults with insomnia showed significant improvements in sleep onset latency, total sleep time, sleep efficiency, and Insomnia Severity Index scores after 10 weeks. A 2012 RCT (Auddy et al.) demonstrated a 27.9% reduction in serum cortisol and significant reductions in PSS-10 scores versus placebo at 60 days.

Q: Does PhytoCann BP cause any psychotropic effects like cannabis?
A: No. Beta-caryophyllene is a selective CB2 agonist with no affinity for the CB1 receptor — the receptor responsible for the psychoactive ("high") effects of THC. It is a naturally occurring terpene in black pepper, hops, and cloves classified as a dietary phytocannabinoid. PhytoCann BP does not produce intoxication, impair cognition, or result in positive drug screening for cannabinoids.

Q: Can Nrv2 be taken alongside sleeping pills or anti-anxiety medications?
A: Ashwagandha's cortisol-lowering and GABA-modulating effects may potentiate benzodiazepines, Z-drugs (zolpidem, zopiclone), or sedative antihistamines. Maizinol's melatonin-pathway activity may interact with prescribed melatonin or melatonin receptor agonists. Consult your Singapore-registered GP or psychiatrist before combining Nrv2 with any prescription sedative, anxiolytic, or hypnotic medication.

Q: When is the best time to take Nrv2 for sleep support?
A: For sleep support, evening dosing 30–60 minutes before bedtime aligns with the melatonin secretion window (approximately 9–11pm for most adults). For general stress support, split dosing (one capsule morning, one evening) is used in some ashwagandha RCT protocols. Follow the current product label dosage instructions; consult a healthcare professional for personalised advice.

Q: Is SRW Nrv2 available with a prescription in Singapore?
A: SRW Nrv2 is a dietary supplement and does not require a prescription in Singapore. It is available directly from EMIS+ at emis.asia with islandwide delivery. The product complies with Singapore Food Regulations and the Health Products Act. EMIS+ can provide product documentation for corporate wellness procurement or clinical protocol reference.