Dr Berg
Dr. Berg Sleep Aid Regular Formula - Achieve Restful Nights with 90 Capsules
Dr. Berg Sleep Aid Regular Formula - Achieve Restful Nights with 90 Capsules
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Product Overview
Dr. Berg Sleep Aid Regular Formula addresses the neuroendocrine contributors to disrupted sleep rather than relying on exogenous melatonin or synthetic sedatives. L-theanine — an amino acid derivative found in Camellia sinensis leaf — promotes alpha-wave brain activity and reduces anxiety-related sleep latency without impairing REM architecture. Tryptophan serves as a direct serotonin and melatonin precursor, supporting endogenous melatonin production through the tryptophan–serotonin–melatonin biosynthetic pathway. GABA (gamma-aminobutyric acid), the primary inhibitory neurotransmitter of the central nervous system, reduces neuronal excitability during sleep initiation. Fo-ti root extract (Polygonum multiflorum, 24:1 concentration) contributes adaptogenic properties relevant to cortisol-mediated sleep disruption.
Bovine adrenal and pituitary glandular concentrates provide co-factors supporting hypothalamic-pituitary-adrenal (HPA) axis normalisation, which is clinically relevant in individuals with elevated evening cortisol. Rehmannia glutinosa (25 mg) functions as a complementary adaptogen with documented activity in traditional pharmacopoeias including the Chinese Pharmacopoeia 2020 edition. Each batch is produced under current Good Manufacturing Practice (cGMP) standards at an NSF International-certified facility and is accompanied by a certificate of analysis (CoA) confirming third-party verification of heavy metal limits (lead, arsenic, cadmium, mercury) and microbial safety parameters, consistent with United States Pharmacopeia (USP) Chapter <2232> elemental contaminants guidance.
Specifications
| Attribute | Detail |
|---|---|
| Manufacturer | Dr. Berg Nutritionals (USA) |
| Format | Hard gelatin capsules; 90 capsules per container |
| Serving Size | 1 capsule; 90 servings per container |
| Key Actives per Serving | Fo-ti root extract 24:1 (119 mg), L-theanine (100 mg), Tryptophan (100 mg), GABA (25 mg), Glycine (25 mg), DMAE bitartrate (25 mg), Rehmannia root (25 mg), Bovine adrenal substance (10 mg), Adrenal pituitary substance (500 mcg) |
| Micronutrients | Vitamin C 3 mg, Niacin (niacinamide) 18 mg, Calcium (lactate) 7 mg, Magnesium (citrate) 8 mg, Choline (bitartrate) 4 mg |
| Excipients | Magnesium stearate (vegetable), silicon dioxide; gelatin capsule shell |
| Allergen Status | Contains bovine glandular extracts (non-vegan); gelatin capsule (non-vegan) |
| Melatonin Content | None — melatonin-free formulation |
| Manufacturing Standard | US cGMP (21 CFR Part 111); NSF International certified facility |
| Third-Party Testing | Certificate of Analysis (CoA) — heavy metals and microbial safety per USP standards |
| Recommended Use | 1 capsule before bed; not for use in children under 18 |
| Storage | Store below 25°C in a cool, dry place; keep container tightly closed |
Clinical Indications and Applications
- Stress-Induced Sleep Onset Difficulty: Indicated for adults experiencing difficulty initiating sleep attributable to elevated evening cortisol or adrenal hyperactivity, where pharmacological sedatives are not clinically warranted and a non-dependency-forming alternative is preferred.
- Circadian Rhythm Support Without Melatonin Dependency: Suitable for shift workers, frequent travellers, and individuals with irregular circadian schedules who wish to avoid exogenous melatonin, which can suppress endogenous pineal melatonin production with chronic use per European Sleep Research Society (ESRS) guidance.
- HPA Axis Support in Subclinical Stress States: Bovine adrenal and pituitary glandular concentrates support HPA axis normalisation, relevant in subclinical adrenal stress patterns and elevated evening salivary cortisol identified on functional health assessments.
- Serotonin Precursor Supplementation in Low-Tryptophan States: Appropriate as an adjunct nutritional strategy in individuals with documented dietary tryptophan insufficiency, supporting both mood regulation and endogenous melatonin synthesis.
- Non-Pharmacological Adjunct to CBT-I Programmes: May be used alongside structured Cognitive Behavioural Therapy for Insomnia (CBT-I) programmes recommended by the American Academy of Sleep Medicine (AASM) for chronic insomnia disorder (DSM-5 code 780.52).
Frequently Asked Questions
Q: Why is this formulation melatonin-free and what are the clinical implications?
A: Exogenous melatonin can down-regulate endogenous pineal melatonin synthesis with prolonged use, a concern noted by the European Sleep Research Society (ESRS). This formulation instead supplies tryptophan as an endogenous melatonin precursor, supporting physiological melatonin production without suppressing the pineal axis, making it appropriate for long-term use under clinical guidance.
Q: Is this product appropriate for individuals taking SSRIs or serotonergic medications?
A: Tryptophan supplementation in patients taking selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) carries a theoretical risk of serotonin syndrome. Healthcare practitioners should evaluate this risk individually and implement a graduated dose protocol with monitoring before recommending concurrent use, as per Singapore MOH prescribing guidelines for drug-nutrient interactions.
Q: What does NSF International certification confirm for procurement purposes?
A: NSF International is an accredited public health and safety organisation certifying dietary supplements against contamination with prohibited substances, heavy metals, and microbial pathogens under NSF/ANSI 173 standards. Certification provides procurement assurance for Singapore clinics, corporate wellness programmes, and occupational health providers requiring third-party quality verification.
Q: Is this supplement registered with the Health Sciences Authority (HSA) Singapore?
A: Health supplements in Singapore are regulated under the Health Products Act (HPA). Products not containing controlled substances are classified as health supplements for general sale under HSA's regulatory framework. Dr. Berg Sleep Aid contains no scheduled or controlled substances and complies with Singapore's health supplement sale regulations under the Health Products Act (General Sale List).
Q: Where can Singapore healthcare providers and wellness centres procure this product in bulk?
A: Essential Medical International Supplies (EMIS) at emis.asia provides B2B procurement with direct invoicing for registered Singapore clinics, corporate wellness programmes, and occupational health providers. Bulk orders and corporate account arrangements are available — contact EMIS via emis.asia for pricing and account setup.
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