• SRW Cel³ Renewal Advanced Cellular Health & Anti Aging Formula
  • Cel³ Renewal
  • Cel³ Renewal
  • Cel³ Renewal
  • Cel³ Renewal
  • Cel³ Renewal
1 6

Science Research Wellness: SRW

SRW Cel³ Renewal Advanced Cellular Health & Anti Aging Formula

SRW Cel³ Renewal Advanced Cellular Health & Anti Aging Formula

$172.00 SGD
$345.00 SGD $172.00 SGD
促销 售罄
结账时计算的运费。
Clinical Summary: SRW Cel³ Renewal is a senolytic and cellular renewal nutraceutical formulated by Science Research Wellness (New Zealand), containing a proprietary blend of fisetin (from Cotinus coggygria, 10%), oleuropein (from Olea europaea, 40%), EGCG (from Camellia sinensis, 50%), berberine (from Cortex phellodendri, 50%), withaferin A (from Ashwagandha, 5%), alpha lipoic acid, and apigenin (100 mg). The formulation targets senescent cell clearance, autophagy activation, and cellular housekeeping pathways analogous to fasting-mimetic mechanisms. Manufactured under GMP-certified, ISO 22000-compliant conditions with published clinical trial support.

Product Overview

SRW Cel³ Renewal is a scientifically formulated cellular renewal supplement developed by Science Research Wellness, a New Zealand biotechnology company specialising in longevity and cellular health nutraceuticals. The product was formulated by Dr. Chris Meletis, a naturopathic physician with over 250 published scientific articles and 12 books on nutraceutical science. Cel³ targets three interconnected hallmarks of ageing: cellular senescence (the accumulation of dysfunctional “zombie” cells that secrete pro-inflammatory cytokines), impaired autophagy (reduced cellular waste clearance), and dysregulated nutrient sensing.

The formulation employs a multi-compound senolytic and autophagy-activating strategy. Fisetin, the primary senolytic agent, has demonstrated selective clearance of senescent cells in preclinical models published in EBioMedicine (2018). Apigenin supports NAD+ homeostasis and autophagy induction, while oleuropein from olive leaf extract promotes the natural recycling of cellular components. The combined mechanism mirrors aspects of intermittent fasting at the cellular level, supporting cellular housekeeping without caloric restriction. The SRW Cel System has been evaluated in a 12-month clinical trial published in Frontiers in Aging (2024).

Specifications

Manufacturer SRW Laboratories (Science Research Wellness), New Zealand
Product Code Cel³ Renewal
Proprietary Blend 1,100 mg per 2-capsule serve
Key Active: Fisetin Cotinus coggygria extract standardised to 10% fisetin — natural senolytic compound
Key Active: Oleuropein Olea europaea (olive leaf) extract standardised to 40% oleuropein — autophagy support
Key Active: EGCG Camellia sinensis extract standardised to 50% EGCG — cellular protection
Key Active: Berberine Cortex phellodendri extract standardised to 50% berberine — AMPK activation and nutrient sensing
Key Active: Withaferin A Ashwagandha extract standardised to 5% withaferin A — senolytic and adaptogenic support
Additional Actives Alpha Lipoic Acid; Apigenin 100 mg
Capsule Type Delayed-release vegetarian capsule (60 per bottle)
Dosage 2 capsules daily with food, or as directed by healthcare practitioner
Manufacturing Standard GMP-certified facility; ISO 22000 Food Safety Management compliant
Regulatory Status Listed dietary supplement (New Zealand MPI); compliant with Singapore HSA Health Supplement guidelines
Clinical Evidence 12-month clinical trial (Frontiers in Aging, 2024; PMC11984428)
Allergens Free from gluten, dairy, soy, and artificial colours

Clinical Indications and Key Applications

  • Senolytic support for adults aged 35 and above seeking to reduce the burden of senescent cells associated with chronic low-grade inflammation (inflammaging)
  • Autophagy activation and cellular waste clearance support for individuals unable to maintain regular intermittent fasting protocols
  • Complementary cellular renewal support alongside anti-ageing, exercise, and dietary optimisation programmes
  • AMPK pathway activation via berberine for individuals seeking metabolic efficiency and nutrient-sensing regulation
  • Antioxidant and cellular protection support for individuals exposed to chronic environmental stressors (UV, pollution, psychological stress)
  • Adjunctive nutritional support for longevity-focused health protocols when used in combination with SRW Cel¹ Stability and Cel² Nourishment

Frequently Asked Questions

Q: What are senolytic compounds and how does fisetin work?

A: Senolytic compounds selectively target and promote the clearance of senescent cells — aged, dysfunctional cells that resist normal apoptosis and accumulate with age, secreting pro-inflammatory factors (the senescence-associated secretory phenotype, or SASP). Fisetin, a naturally occurring flavonoid, has demonstrated senolytic activity in preclinical research published in EBioMedicine (2018), showing selective reduction of senescent cell markers in multiple tissue types without affecting healthy proliferating cells.

Q: How does Cel³ mimic the effects of fasting?

A: Several active ingredients in Cel³ activate cellular pathways typically induced by caloric restriction or intermittent fasting. Berberine activates AMPK (AMP-activated protein kinase), a key metabolic sensor triggered during energy deficit states. Oleuropein and EGCG support autophagy — the cellular self-cleaning process upregulated during fasting. Apigenin supports NAD+ levels, further enhancing the cellular energy-sensing cascade. Together, these compounds provide fasting-mimetic cellular benefits without requiring dietary restriction.

Q: Is this product suitable for concurrent use with prescription medications?

A: Berberine has documented interactions with CYP450 enzyme substrates, including certain statins, antidiabetic medications, and immunosuppressants. EGCG may affect iron absorption and certain hepatically metabolised drugs. Individuals taking prescription medications should consult their healthcare practitioner before commencing Cel³, particularly those on metformin, warfarin, or CYP3A4 substrates.

Q: What is the recommended protocol for the full SRW Cel System?

A: The SRW Cel System comprises Cel¹ Stability (genomic protection and telomere maintenance), Cel² Nourishment (NAD+ and mitochondrial energy), and Cel³ Renewal (senolytic clearance and autophagy). Used together, the three formulations address multiple hallmarks of ageing as defined by López-Otín et al. (Cell, 2013; updated 2023). The 12-month clinical trial evaluated the combined protocol and reported significant improvements in epigenetic age markers.

Q: Is Cel³ Renewal registered with Singapore health authorities?

A: Cel³ is manufactured in a GMP-certified, ISO 22000-compliant facility in New Zealand and complies with Singapore Health Sciences Authority (HSA) guidelines for health supplements. As a dietary supplement, it does not require HSA pre-market approval. It is imported and distributed by EMIS Pte Ltd in accordance with Singapore Food Agency (SFA) import regulations.

查看完整详细信息