Magnesium L Threonate 2000 mg Brain Support Supplement by Sports Research

Product Overview

Sports Research Magnesium L-Threonate is a brain-health supplement featuring the patented Magtein compound — a novel magnesium salt formed from magnesium and threonic acid (a metabolite of vitamin C). Developed by a team of neuroscientists at the Massachusetts Institute of Technology (MIT), Magtein is the only magnesium compound that has been shown in preclinical and clinical studies to effectively cross the blood-brain barrier and elevate magnesium levels within the central nervous system. Each daily serving of three veggie capsules provides 2000 mg of magnesium L-threonate, yielding approximately 144 mg of elemental magnesium.

The product is manufactured in a cGMP-compliant, FDA-registered facility in the United States and is verified Non-GMO Project certified. The capsule shell is made from hypromellose (vegetable cellulose), making it suitable for vegetarian and vegan diets. Sports Research sources the Magtein raw material exclusively from AIDP Inc., the licensed patent holder, ensuring authenticity and consistent potency. The formulation contains no artificial colours, flavours, or preservatives, and is free from gluten, soy, dairy, and common allergens.

Specifications

Clinical Indications

• Support for cognitive function and memory consolidation — Magtein has been shown in clinical trials (published in the Journal of Alzheimer's Disease) to improve episodic memory and executive function in adults aged 50–70
• Enhancement of synaptic plasticity and neuronal signalling — magnesium is a critical cofactor for NMDA receptor function, which underlies learning and memory at the synaptic level
• Support for healthy sleep architecture — magnesium modulates GABAergic neurotransmission and hypothalamic-pituitary-adrenal (HPA) axis activity, contributing to sleep quality
• Cognitive support in age-related magnesium depletion — approximately 50% of adults consume less than the estimated average requirement (EAR) for magnesium, with intracellular deficiency increasing with age
• Mood and stress response support — magnesium participates in over 300 enzymatic reactions including those regulating cortisol metabolism and serotonin synthesis

Frequently Asked Questions

Q: Why is magnesium L-threonate preferred over other magnesium forms for brain health?
A: Most magnesium supplements (oxide, citrate, glycinate) have limited ability to cross the blood-brain barrier. Research published in Neuron by MIT scientists demonstrated that magnesium L-threonate (Magtein) uniquely increases magnesium concentration in the cerebrospinal fluid and brain tissue, enhancing synaptic density and plasticity in the hippocampus and prefrontal cortex — regions critical for memory and executive function.

Q: What clinical evidence supports Magtein for cognitive function?
A: A randomised, double-blind, placebo-controlled clinical trial published in the Journal of Alzheimer's Disease (2016) demonstrated that 12 weeks of Magtein supplementation significantly improved composite memory scores, attention, and executive function in adults aged 50–70 with subjective cognitive complaints. Brain age was effectively reversed by an average of 9.4 years based on cognitive testing metrics.

Q: Can magnesium L-threonate be taken with other magnesium supplements?
A: Yes, though total daily magnesium intake should be monitored. Each serving of this product provides approximately 144 mg elemental magnesium (34% of the recommended daily value). The tolerable upper intake level (UL) for supplemental magnesium established by the National Academy of Medicine is 350 mg/day. Individuals taking additional magnesium supplements should consult their healthcare practitioner to avoid exceeding recommended intake levels.

Q: Is this product available for purchase in Singapore?
A: Yes. Magnesium L-threonate supplements are classified as health supplements under the Singapore Health Sciences Authority (HSA) Health Supplements Guidelines. This product is manufactured in an FDA-registered cGMP facility and meets the quality standards required for import into Singapore. EMIS provides direct delivery within Singapore with proper documentation.

Q: What is the recommended time to take magnesium L-threonate?
A: Sports Research recommends taking 3 capsules daily with food. Many clinicians suggest dividing the dose — 1 capsule in the morning and 2 capsules in the evening — as magnesium's effects on GABAergic neurotransmission may support relaxation and sleep quality when taken in the evening hours. However, the full daily dose can be taken at any single time point with a meal.