EMIS +
Metabolic Engine Tracker
Metabolic Engine Tracker
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Product Overview
The EMIS+ Metabolic Engine Tracker employs indirect calorimetry, the clinical reference standard for measuring resting metabolic rate (RMR), combined with a targeted blood biomarker panel to provide a comprehensive metabolic health assessment. Indirect calorimetry measures oxygen consumption (VO2) and carbon dioxide production (VCO2) through breath analysis, calculating respiratory exchange ratio (RER) to determine the proportion of energy derived from carbohydrate versus fat oxidation. This methodology is endorsed by the American College of Sports Medicine (ACSM) and validated against the Weir equation (ISO 80601-2-55) for metabolic rate determination.
The accompanying blood panel assesses fasting glucose, fasting insulin, HbA1c, lipid profile (total cholesterol, LDL, HDL, triglycerides), thyroid function (TSH, free T3, free T4), cortisol, and inflammatory markers (hs-CRP). These biomarkers are analysed by CAP-accredited and ISO 15189-certified laboratories in Singapore. Results are interpreted by qualified healthcare professionals and integrated into a personalised metabolic optimisation plan addressing nutrition, exercise prescription, sleep, and stress management aligned with Singapore Ministry of Health preventive health guidelines.
Specifications
| Provider | EMIS+ Singapore |
| Assessment Components | Indirect calorimetry (RMR) + blood biomarker panel + body composition metrics |
| Metabolic Measurements | Resting metabolic rate (kcal/day), respiratory exchange ratio (RER), substrate oxidation rates (g/min fat and carbohydrate) |
| Blood Biomarkers | Fasting glucose, fasting insulin, HbA1c, HOMA-IR, lipid panel, TSH, free T3/T4, cortisol, hs-CRP |
| Methodology | Open-circuit indirect calorimetry per Weir equation; venous blood draw analysed by ISO 15189-certified laboratory |
| Assessment Duration | Approximately 60–90 minutes (includes fasting breath test and blood draw) |
| Fasting Requirement | 10–12 hour overnight fast; no caffeine or vigorous exercise 24 hours prior |
| Reference Standards | ISO 80601-2-55 (respiratory gas analysers); ISO 15189 (medical laboratories); ACSM metabolic testing guidelines |
| Regulatory Framework | HSA Singapore registered medical devices; laboratory services licensed under MOH Singapore Private Hospitals and Medical Clinics Act |
| Report Delivery | Digital report within 3–5 working days with clinical interpretation and personalised recommendations |
| Quality Assurance | CAP-accredited laboratory; equipment calibrated per manufacturer ISO 17025 protocols |
Clinical Indications
- Metabolic syndrome screening by quantifying insulin resistance (HOMA-IR), dyslipidaemia, and central adiposity markers in accordance with IDF and ATP III diagnostic criteria
- Weight management programme design through precise RMR measurement, enabling evidence-based caloric prescription rather than estimation-based approaches
- Thyroid function assessment to identify subclinical hypothyroidism or hyperthyroidism contributing to metabolic dysfunction
- Athletic performance profiling to determine fuel utilisation efficiency, fat oxidation capacity, and metabolic flexibility during rest and exercise
- Type 2 diabetes risk stratification using fasting insulin, HbA1c, and glucose-insulin dynamics aligned with ADA and MOH Singapore clinical practice guidelines
- Longevity health baseline assessment for adults seeking to optimise mitochondrial function, inflammatory status, and hormonal balance through data-driven interventions
Frequently Asked Questions
What is the difference between estimated and measured metabolic rate?
Estimation equations such as Harris-Benedict and Mifflin-St Jeor predict metabolic rate from age, sex, height, and weight, but these formulae carry prediction errors of 10–30% at the individual level. Indirect calorimetry, as used in the Metabolic Engine Tracker, directly measures oxygen consumption and carbon dioxide production to calculate actual metabolic rate with a precision error below 5%. The American College of Sports Medicine (ACSM) recommends measured RMR for clinical nutrition planning.
What does the respiratory exchange ratio (RER) reveal?
The respiratory exchange ratio is the ratio of CO2 produced to O2 consumed during metabolism. An RER of 0.7 indicates predominant fat oxidation, while 1.0 indicates predominant carbohydrate oxidation. Values between 0.7 and 1.0 reflect mixed substrate utilisation. This metric helps identify metabolic inflexibility, a condition associated with insulin resistance and metabolic syndrome, and guides nutrition interventions to improve fat oxidation capacity.
How should I prepare for the metabolic assessment?
Patients must fast for 10–12 hours before the assessment (water is permitted). Avoid caffeine, alcohol, and vigorous exercise for 24 hours prior. Arrive in a rested state and wear comfortable clothing. These standardised conditions, recommended by ACSM metabolic testing protocols, ensure accurate baseline measurements of metabolic rate and substrate utilisation.
Who benefits most from a metabolic health assessment in Singapore?
Individuals with unexplained weight gain or difficulty losing weight, those with family history of metabolic syndrome or type 2 diabetes, athletes seeking to optimise fuel efficiency, and adults pursuing preventive longevity health strategies. Singapore's multiethnic population has varying metabolic risk profiles, and the Ministry of Health identifies metabolic disease as a national health priority, making personalised metabolic assessment particularly relevant.
How often should metabolic testing be repeated?
For individuals undergoing dietary, exercise, or pharmacological interventions, repeat assessment at 3–6 month intervals provides meaningful data on metabolic adaptation. Stable individuals may benefit from annual reassessment to track age-related metabolic changes. Serial testing enables clinicians to quantify intervention efficacy and adjust recommendations based on objective metabolic data rather than subjective outcomes.